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Assisted Embryo Hatching
The outer shell of the embryo (called the Zona Pellucida) can sometimes
become hardened and thickened, especially in older women, resulting in
the embryo having difficulty in being released to attach to the uterus.
It is possible to make an opening in the zona pellucida to help the embryo
escape from its shell. This is called Assisted Hatching. It is done in
one of two ways, by either cutting a slit in the zona using a fine glass
needle or by drilling a hole in the zona using acidic culture medium.
Assisted hatching can be performed on fresh embryos and thawed embryos.
Currently, hatched embryos will not be frozen as they do not thaw successfully.
At this stage published research work is conflicting with some studies
showing definite improvements in pregnancy rates from this procedure whilst
other research shows no benefits.
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